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Theoretical Modelling

By GlasgowUni 2011

During our project DISColi, regarding Bio-photolithography in biofilms, we created mathematical models involving Latherin and its rate of diffusion through a biofilm. We are presenting our findings in Figure 1 and Table 1. Also, due to the mode of action of Latherin the attainable spatial resolution seems to be less than 0.08 mm. For more information, please visit GlasgowUni 2011 Wiki

Figure.1. Relative One-dimensional Diffusion of (a)Latherin at certain points in time and (b)Latherin within first 60 min. Threshold indicates critical concentration required for the molecule to work.

(a)

(b)

Table 1. Details on Latherin

Name of molecule	Length (a.a.)	Molecular weight (g/mol)	Diffusion rate (mm2/min)	Critical concentration (molecules)	Translation rate (molecule/min)	Achieving Critical Concentration (min)
Latherin	220	24400	1.38*10-4	173	46.9	3